Opgericht: 24 mei 1927.
Kampioen Chili (17 keer): 1940, 1959, 1962, 1964, 1965, 1967, 1969, 1994, 1995, 1999, 2000, 2004 (Apertura), 2009 (Apertura), 2011 (Apertura), 2011 (Clausura), 2012 (Apertura) en 2014 (Apertura).
Bekerwinnaar (4 keer): 1979, 1998, 2000 en 2013.
Copa Sudamericana (1 keer): 2011.
Groep 4, Copa Libertadores 2015
| Pos | Club | Opmerking | Kleur | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Sport Club Internacional | Achtste Finale | #4eee37 | 6 | 4 | 1 | 1 | 13 | 7 | 6 | 13 |
| 2 |  Club Sport Emelec | Achtste Finale | #4eee37 | 6 | 3 | 1 | 2 | 9 | 5 | 4 | 10 |
| 3 |  The Strongest | - | - | 6 | 3 | 0 | 3 | 10 | 11 | -1 | 9 |
| 4 | Club Universidad de Chile | - | - | 6 | 1 | 0 | 5 | 7 | 16 | -9 | 3 |
Chileense Primera Division: Apertura 2015/2016
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Colo-Colo | 15 | 11 | 0 | 4 | 24 | 14 | 10 | 33 |
| 2 |  Club Deportivo Universidad Católica | 15 | 10 | 2 | 3 | 33 | 15 | 18 | 32 |
| 3 |  C.D. Universidad de Concepción | 15 | 9 | 1 | 5 | 29 | 19 | 10 | 28 |
| 4 |  Club Deportivo Palestino | 15 | 8 | 4 | 3 | 23 | 17 | 6 | 28 |
| 5 |  Audax Italiano | 15 | 7 | 5 | 3 | 22 | 19 | 3 | 26 |
| 6 |  Unión Española | 15 | 7 | 3 | 5 | 30 | 20 | 10 | 24 |
| 7 |  O’Higgins FC | 15 | 7 | 2 | 6 | 23 | 23 | 0 | 23 |
| 8 |  Santiago Wanderers | 15 | 5 | 5 | 5 | 20 | 19 | 1 | 20 |
| 9 |  Club de Deportes Cobresal | 15 | 6 | 0 | 9 | 23 | 28 | -5 | 18 |
| 10 |  San Marcos de Arica | 15 | 5 | 2 | 8 | 18 | 20 | -2 | 17 |
| 11 | Club Universidad de Chile | 15 | 5 | 6 | 6 | 24 | 30 | -6 | 17 |
| 12 |  Huachipato | 15 | 4 | 4 | 7 | 16 | 21 | -5 | 16 |
| 13 |  Club de Deportes Iquique | 15 | 4 | 4 | 7 | 20 | 28 | -8 | 16 |
| 14 |  Unión La Calera | 15 | 4 | 3 | 8 | 13 | 27 | -14 | 15 |
| 15 |  San Luis de Quillota | 15 | 4 | 1 | 10 | 18 | 24 | -6 | 13 |
| 16 |  Deportes Antofagasta | 15 | 2 | 5 | 8 | 11 | 22 | -11 | 11 |