Bayer 04 Leverkusen 
3 vs 0 
S.S. Lazio
3 vs 0 S.S. LazioRecap
Heenwedstrijd 0-1
Toeschouwers: 28.222.
Scheidsrechter: Carlos Velasco Carballo (Spanje).
Scoreverloop:
1-0 Hakan Çalhanoglu 40.
2-0 Admir Mehmedi 48.
3-0 Karim Bellarabi 88. (assist Julian Brandt)
S.S. Lazio: Marco Parolo (71), Senad Lulic (74)
S.S. Lazio: Mauricio (60+68)
Bayer 04 Leverkusen
| 1 | Bernd Leno Keeper | |
| 13 | Roberto Hilbert Verdediger | (86) |
| 4 | Jonathan Tah Verdediger | |
| 5 | Kyriakos Papadopoulos Verdediger | |
| 18 | Wendell Nascimento Borges Verdediger | (67) |
| 38 | Karim Bellarabi 2 Middenvelder |  (89) (88) (37) |
| 23 | Christoph Kramer Middenvelder | |
| 8 | Lars Bender Middenvelder | |
| 10 | Hakan Çalhanoğlu 27 Middenvelder | (80) (40) |
| 11 | Stefan Kießling Aanvaller | |
| 14 | Admir Mehmedi 19 Aanvaller | (76) (48) |
| 19 | Julian Brandt 14 Middenvelder |  (76) |
| 27 | Robbie Kruse 10 Middenvelder | (80) |
| 2 | André Ramalho da Silva 38 Middenvelder | (89) |
| 17 | Sebastian Boenisch Verdediger | |
| 24 | Seung-Woo Ryu Middenvelder | |
| 25 | Dario Krešić Keeper | |
| 26 | Giulio Donati Verdediger | |
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Trainer: Roger Schmidt
S.S. Lazio
| 99 | Etrit Berisha Keeper | |
| 3 | Stefan de Vrij Verdediger | |
| 8 | Dušan Basta Verdediger | |
| 26 | Stefan Radu 88 Verdediger | (56) |
| 87 | Antonio Candreva Middenvelder | |
| 88 | Ricardo Kishna 26 Aanvaller | (56) |
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Gewisseld
Ingevallen
Goals
Penalty
Penalty Gemist
Yellow Cards
Yellow/Red Card
Red Cards
| 3 | 1 |
| 3 | 1 |
| 3 | 0 |
| 0 | 0 |
| 0 | 0 |
| 3 | 0 |
| 0 | 0 |
| 0 | 0 |